Is HGH Fragment 176-191 the same as AOD9604?

No. HGH Fragment 176-191 is the native C-terminal 16-residue fragment of human growth hormone (CAS 66004-57-7). AOD9604 is a modified derivative that adds an N-terminal tyrosine to the 177-191 region; the two are distinct molecules and should not be used interchangeably in experimental design.

Are the reported lipolytic effects established?

They are not well established. Independent reviews indicate that lipolytic claims for this fragment have been overstated. We describe it only as a defined GH-derived research peptide and make no efficacy or metabolic claims.

Home CatalogHGH Fragment 176-191

2D Molecular Structure

CID: 16131230
Standard InChIKey: LSTCHEVTSMJOCE-YWWHUHEESA-N
Residue Count: 16 AA
Structural Modifications: C-terminal free acid (–OH)
Cyclic (7→14) intramolecular disulfide

endocrine Research

HGH Fragment 176-191

Also known as: hGH frag 176-191, Somatotropin (176-191), GH (176-191)

C-terminal 16-residue fragment of human growth hormone (residues 176-191) with an internal disulfide bridge, supplied for GH-axis research.

CAS Number: 66004-57-7
Molecular Formula: C78H123N23O22S2
Purity: Batch-specific
Form: Lyophilized powder
Enquiry Sizes: Research vial • Bulk / custom fill (quote required)
Peptide Sequence16 residues: Phe-Leu-Arg-Ile-Val-Gln-Cys-Arg-Ser-Val-Glu-Gly-Ser-Cys-Gly-Phe (disulfide bridge between the two Cys residues)

Compliance Notice: All products supplied by BioTech Pharma are intended strictly for laboratory research and development use only. They are not intended for human or veterinary use, diagnosis, treatment, or consumption of any kind. By submitting an enquiry, the requester confirms they are a qualified researcher or institution and accepts full responsibility for compliant handling and use.

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Batch certificate of analysis (CoA)Full analytical package (HPLC chromatogram + LC-MS data)Lead-time, stock & shipping-condition confirmation

Documentation requests are reviewed against the records available for the applicable lot. Availability, methods, and values must be confirmed for the specific enquiry and are not promised in advance.

Form supplied: Lyophilized powder. Your selections are carried into the quote request automatically.

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Overview

HGH Fragment 176-191 is a 16-residue peptide corresponding to the C-terminal region (residues 176 to 191) of human growth hormone, containing an intramolecular disulfide bridge between its two cysteine residues. The molecular formula (C78H123N23O22S2) and defined sequence are documented in reference chemical records for this specific fragment (CAS 66004-57-7).

This fragment has been used in preclinical and in-vitro studies of growth-hormone structure–function relationships. Popular characterizations of the peptide as a potent lipolytic agent are not well supported; independent reviews note that reported metabolic effects have been overstated. Researchers should treat lipolysis-related descriptions as unverified preclinical claims rather than established pharmacology.

BioTech Pharma supplies HGH Fragment 176-191 as a lyophilized powder offered strictly as a laboratory reference peptide; it is not a drug or a product for human or veterinary use. Lot-specific analytical documentation may be available and should be confirmed for the applicable material.

Research Applications

Growth-hormone C-terminal fragment structure–function studies
GH-axis peptide characterization
Disulfide-bridged peptide chemistry and folding
Comparative fragment vs. full-length GH research
Analytical method development for GH-derived peptides

Frequently Asked Questions

Scientific References

Analytical Data

Lot-specific documentation may be available for the applicable material and must be confirmed per enquiry. Where available, it may include:

HPLC purity result
LC-MS identity confirmation
Appearance
Net content

Request the records you need with your quote and we will confirm availability for your batch.

Procurement Details

Availability, lead time, salt / content basis, and cold-chain requirements depend on the specific lot and quantity, so we confirm them per enquiry rather than publishing fixed figures. Request confirmation for your requirements with your quote and our team will respond with details for the applicable batch.

Storage & Handling

Lyophilized: store sealed at −20 °C, protected from light and moisture. Reconstituted solutions should be kept refrigerated (2–8 °C); the internal disulfide bond makes solution stability lot-specific, and it should be verified empirically for each protocol. Prepared-solution stability should be confirmed for the applicable material.

Related Compounds

Sermorelin Acetate

Amidated GHRH(1-29) analog corresponding to the active N-terminal fragment of growth-hormone-releasing hormone, supplied as the acetate salt.

Tesamorelin

Stabilized GHRH analog used in growth-hormone-axis research, engineered for resistance to enzymatic degradation.

Hexarelin

Synthetic hexapeptide growth-hormone secretagogue related to GHRP-6, studied as a ghrelin-receptor agonist tool compound.