Sermorelin Acetate
Also known as: GRF(1-29) amide, GHRH(1-29), Sermorelin
- CAS Number
- 86168-78-7
- Molecular Formula
- C149H246N44O42S
- Molecular Weight
- 3357.9 g/mol (free base)
- Purity
- Batch-specific
- Form
- Lyophilized powder
- Enquiry Sizes
- Research vial • Bulk / custom fill (quote required)
- Peptide Sequence
- Tyr-Ala-Asp-Ala-Ile-Phe-Thr-Asn-Ser-Tyr-Arg-Lys-Val-Leu-Gly-Gln-Leu-Ser-Ala-Arg-Lys-Leu-Leu-Gln-Asp-Ile-Met-Ser-Arg-NH2
Compliance Notice: All products supplied by BioTech Pharma are intended strictly for laboratory research and development use only. They are not intended for human or veterinary use, diagnosis, treatment, or consumption of any kind. By submitting an enquiry, the requester confirms they are a qualified researcher or institution and accepts full responsibility for compliant handling and use.
Configure Your Request
Documentation requests are reviewed against the records available for the applicable lot. Availability, methods, and values must be confirmed for the specific enquiry and are not promised in advance.
Form supplied: Lyophilized powder. Your selections are carried into the quote request automatically.
Overview
Sermorelin is a synthetic 29-amino-acid amidated peptide, GRF(1-29)-NH2, corresponding to the biologically active N-terminal fragment of the 44-residue human growth-hormone-releasing hormone (GHRH). This N-terminal segment is conserved across several mammalian species and retains GHRH-receptor activity, which is why the truncated analog is used as a research tool for the growth-hormone axis. The molecular formula and weight cited here (C149H246N44O42S; 3357.9 g/mol) correspond to the free-base peptide; the material is supplied as the acetate salt.
In endocrinology research, sermorelin is studied as a GHRH-receptor agonist for probing pulsatile growth-hormone release and downstream IGF-1 axis dynamics in preclinical and in-vitro systems. These are experimental applications; the peptide is offered only as a reference research compound and not as a therapeutic.
BioTech Pharma provides sermorelin acetate as a lyophilized powder for research use only. Because the sequence contains a methionine residue, vials are handled to limit oxidative exposure. Lot-specific analytical documentation may be available and should be confirmed for the applicable material.
Research Applications
- GHRH-receptor agonist signaling studies
- Pulsatile growth-hormone secretion models
- IGF-1 axis dynamics research
- GHRH fragment structure–activity relationships
- Comparative GHRH-analog pharmacology (vs. tesamorelin)
Frequently Asked Questions
Scientific References
Analytical Data
Lot-specific documentation may be available for the applicable material and must be confirmed per enquiry. Where available, it may include:
- HPLC purity result
- LC-MS identity confirmation
- Appearance
- Net content
Request the records you need with your quote and we will confirm availability for your batch.
Procurement Details
Availability, lead time, salt / content basis, and cold-chain requirements depend on the specific lot and quantity, so we confirm them per enquiry rather than publishing fixed figures. Request confirmation for your requirements with your quote and our team will respond with details for the applicable batch.
Storage & Handling
Lyophilized: store sealed at −20 °C, protected from light and moisture; a methionine residue makes minimizing oxidative exposure advisable. Reconstituted solutions should be kept refrigerated (2–8 °C); prepared-solution stability is lot-specific and should be verified for each protocol. Prepared-solution stability should be confirmed for the applicable material.
Related Compounds
Tesamorelin
Stabilized GHRH analog used in growth-hormone-axis research, engineered for resistance to enzymatic degradation.
Hexarelin
Synthetic hexapeptide growth-hormone secretagogue related to GHRP-6, studied as a ghrelin-receptor agonist tool compound.
Ipamorelin
Selective pentapeptide ghrelin-receptor agonist prized in GH-axis research for its clean receptor-selectivity profile.