2D Molecular Structure
- CID
- 71300630
- Standard InChIKey
- GVIYUKXRXPXMQM-BPXGDYAESA-N
- FDA UNII
- 7UP768IP4M
- Residue Count
- 16 AA
- Structural Modifications
- N-terminal Tyr replacing native Phe
- C-terminal free acid (–OH)
- Cys7–Cys14 intramolecular disulfide
AOD-9604
Also known as: AOD9604, Tyr-hGH fragment 176-191, Anti-Obesity Drug 9604
- CAS Number
- 221231-10-3
- Molecular Formula
- C78H123N23O23S2
- Molecular Weight
- ≈ 1815.1 g/mol
- Purity
- Batch-specific
- Form
- Lyophilized powder
- Enquiry Sizes
- Research vial • Bulk / custom fill (quote required)
- Peptide Sequence16 residues
- YLRIVQCRSVEGSCGF (Cys7–Cys14 disulfide)
Compliance Notice: All products supplied by BioTech Pharma are intended strictly for laboratory research and development use only. They are not intended for human or veterinary use, diagnosis, treatment, or consumption of any kind. By submitting an enquiry, the requester confirms they are a qualified researcher or institution and accepts full responsibility for compliant handling and use.
Configure Your Request
Documentation requests are reviewed against the records available for the applicable lot. Availability, methods, and values must be confirmed for the specific enquiry and are not promised in advance.
Form supplied: Lyophilized powder. Your selections are carried into the quote request automatically.
Overview
AOD-9604 is a synthetic 16-residue analogue of the human growth-hormone C-terminal region (residues 176-191) in which tyrosine replaces the fragment’s N-terminal phenylalanine. It carries the disulfide bridge that closes the native loop. It was originally investigated as an anti-obesity candidate; clinical development for that indication was discontinued, so its profile outside cell and animal models is not established pharmacology.
In preclinical research the fragment is studied for its reported ability to influence lipid metabolism in adipocyte and animal systems without the broad growth-hormone-like actions of the full-length hormone. Because it reproduces only the lipolytic region, researchers use it as a tool to dissect which effects of growth hormone map to this specific domain versus the intact protein. Reported metabolic findings are preclinical and should be distinguished from any approved therapeutic use.
BioTech Pharma supplies AOD-9604 as a lyophilized powder for laboratory research use only. Lot-specific analytical documentation may be available and should be confirmed for the applicable material. Bulk and custom-fill quantities are available by quote.
Research Applications
- Lipid-metabolism and adipocyte research models
- Growth-hormone fragment structure–activity studies
- Disulfide-loop peptide chemistry and folding
- Comparative work versus full-length growth hormone
- In-vitro metabolic-signaling assays
Frequently Asked Questions
Scientific References
Analytical Data
Lot-specific documentation may be available for the applicable material and must be confirmed per enquiry. Where available, it may include:
- HPLC purity result
- LC-MS identity confirmation
- Appearance
- Net content
Request the records you need with your quote and we will confirm availability for your batch.
Procurement Details
Availability, lead time, salt / content basis, and cold-chain requirements depend on the specific lot and quantity, so we confirm them per enquiry rather than publishing fixed figures. Request confirmation for your requirements with your quote and our team will respond with details for the applicable batch.
Storage & Handling
Lyophilized: store desiccated at −20 °C, protected from light. Reconstituted: keep at 2–8 °C and establish working-solution stability empirically per lot; the internal disulfide makes prepared solutions sensitive to reducing conditions and repeated handling.
Related Compounds
Tesamorelin
Stabilized GHRH analog used in growth-hormone-axis research, engineered for resistance to enzymatic degradation.
CJC-1295 with DAC
Long-acting GHRH analogue bearing a maleimidopropionyl-lysine drug-affinity complex that binds albumin, studied in GH-axis research.
GHRP-6
First-generation synthetic hexapeptide ghrelin-receptor agonist, a classic reference secretagogue in growth-hormone research.