2D Molecular Structure
- CID
- 9941379
- Standard InChIKey
- FFHBJDQSGDNCIV-MFVUMRCOSA-N
- FDA UNII
- 6Y24O4F92S
- Residue Count
- 7 AA
- Structural Modifications
- N-terminal acetyl (Ac-Nle1); C-terminal free acid (–OH)
- Cyclic (2→7) side-chain lactam bridge (Asp2 β-carboxyl to Lys7 ε-amine)
- PubChem record is the bremelanotide free base
PT-141 (Bremelanotide)
Also known as: Bremelanotide, PT-141
- CAS Number
- 189691-06-3
- Molecular Formula
- C50H68N14O10
- Molecular Weight
- ≈ 1025.2 g/mol
- Purity
- Batch-specific
- Form
- Lyophilized powder
- Enquiry Sizes
- Research vial • Bulk / custom fill (quote required)
- Peptide Sequence7 residues
- Ac-Nle-Asp-His-D-Phe-Arg-Trp-Lys-OH (cyclic 2→7 side-chain lactam between Asp2 and Lys7)
Compliance Notice: All products supplied by BioTech Pharma are intended strictly for laboratory research and development use only. They are not intended for human or veterinary use, diagnosis, treatment, or consumption of any kind. By submitting an enquiry, the requester confirms they are a qualified researcher or institution and accepts full responsibility for compliant handling and use.
Configure Your Request
Documentation requests are reviewed against the records available for the applicable lot. Availability, methods, and values must be confirmed for the specific enquiry and are not promised in advance.
Form supplied: Lyophilized powder. Your selections are carried into the quote request automatically.
Overview
PT-141 (bremelanotide) is a cyclic seven-residue peptide melanocortin-receptor agonist derived from the α-melanocyte-stimulating hormone (α-MSH) lineage, and a metabolite-based successor to the earlier compound melanotan II. It acts across melanocortin receptor subtypes, with research interest centered on melanocortin-4 receptor (MC4R) signaling. It is an established, approved drug for a specific human indication, which distinguishes its clinical pharmacology from the exploratory, non-clinical work described here.
As a research reagent it is used to probe melanocortin-receptor pharmacology, receptor-subtype selectivity, and downstream signaling in cell and animal models. Because its structure and receptor activity are extensively documented, it serves as a convenient reference agonist when characterizing newer melanocortin ligands. Any laboratory findings on behavior or physiology in preclinical systems should be reported as preclinical and kept separate from its established, indication-specific human pharmacology.
BioTech Pharma supplies PT-141 as a lyophilized powder for laboratory research use only. Lot-specific analytical documentation may be available and should be confirmed for the applicable material. Bulk and custom-fill quantities are available by quote.
Research Applications
- Melanocortin-receptor (MC1R–MC5R) pharmacology
- MC4R signaling and receptor-selectivity studies
- α-MSH-family structure–activity research
- Reference-agonist comparative screening
- Cyclic-peptide chemistry and stability
Frequently Asked Questions
Scientific References
Analytical Data
Lot-specific documentation may be available for the applicable material and must be confirmed per enquiry. Where available, it may include:
- HPLC purity result
- LC-MS identity confirmation
- Appearance
- Net content
Request the records you need with your quote and we will confirm availability for your batch.
Procurement Details
Availability, lead time, salt / content basis, and cold-chain requirements depend on the specific lot and quantity, so we confirm them per enquiry rather than publishing fixed figures. Request confirmation for your requirements with your quote and our team will respond with details for the applicable batch.
Storage & Handling
Lyophilized: store desiccated at −20 °C, protected from light. Reconstituted: keep at 2–8 °C and determine working-solution stability empirically per lot, as prepared-solution stability varies with diluent and handling.
Related Compounds
Kisspeptin-10
KISS1-derived decapeptide and master regulator of the reproductive axis — the key tool compound in GnRH-pathway research.
GHK-Cu
Naturally occurring copper tripeptide complex, central to dermal-matrix, collagen-synthesis, and cosmetic-formulation research.
Semax
ACTH(4-7)-derived heptapeptide investigated in neuroprotection, cognitive-performance, and BDNF-pathway research.