2D Molecular Structure
- CID
- 9811102
- Standard InChIKey
- AFEHBIGDWIGTEH-AQRCPPRCSA-N
- FDA UNII
- I5FAL2585H
- Residue Count
- 7 AA
- Structural Modifications
- ACTH(4-7) fragment (Met-Glu-His-Phe) extended with a C-terminal Pro-Gly-Pro tail
- Contains one methionine (oxidation-sensitive); free N- and C-termini
Semax
- CAS Number
- 80714-61-0
- Molecular Formula
- C37H51N9O10S
- Molecular Weight
- 813.9 g/mol
- Purity
- Batch-specific
- Form
- Lyophilized powder
- Enquiry Sizes
- 5 mg • 10 mg • Bulk (gram+)
- Peptide Sequence7 residues
- Met-Glu-His-Phe-Pro-Gly-Pro
Compliance Notice: All products supplied by BioTech Pharma are intended strictly for laboratory research and development use only. They are not intended for human or veterinary use, diagnosis, treatment, or consumption of any kind. By submitting an enquiry, the requester confirms they are a qualified researcher or institution and accepts full responsibility for compliant handling and use.
Configure Your Request
Documentation requests are reviewed against the records available for the applicable lot. Availability, methods, and values must be confirmed for the specific enquiry and are not promised in advance.
Form supplied: Lyophilized powder. Your selections are carried into the quote request automatically.
Overview
Semax is a synthetic heptapeptide combining the ACTH(4-7) fragment (Met-Glu-His-Phe) with a C-terminal Pro-Gly-Pro sequence that confers resistance to enzymatic breakdown. Unlike full-length ACTH, Semax exhibits no meaningful corticotropic (hormonal) activity, isolating the neurotropic properties of the fragment.
It is one of the most studied nootropic-class peptides in the literature, with research covering BDNF and NGF expression, attention and memory paradigms, and neuroprotection in ischemia models. These are preclinical observations that do not establish clinical efficacy.
BioTech Pharma supplies Semax as a lyophilized powder for laboratory research use only; because the sequence contains methionine, handling that limits oxidative exposure is advisable. Lot-specific analytical documentation may be available and should be confirmed for the applicable material.
Research Applications
- BDNF and NGF expression studies
- Attention and memory behavioral paradigms
- Ischemia and neuroprotection models
- Melanocortin-fragment pharmacology
- Comparative nootropic-peptide characterization
Frequently Asked Questions
Scientific References
Analytical Data
Lot-specific documentation may be available for the applicable material and must be confirmed per enquiry. Where available, it may include:
- HPLC purity result
- LC-MS identity confirmation
- Appearance
- Net content
Request the records you need with your quote and we will confirm availability for your batch.
Procurement Details
Availability, lead time, salt / content basis, and cold-chain requirements depend on the specific lot and quantity, so we confirm them per enquiry rather than publishing fixed figures. Request confirmation for your requirements with your quote and our team will respond with details for the applicable batch.
Storage & Handling
Lyophilized: store at −20 °C, protected from light. Reconstituted: keep at 2–8 °C and determine working-solution stability empirically per lot, as reconstituted stability varies with diluent, concentration, and handling.
Related Compounds
Selank
Synthetic tuftsin-analog heptapeptide studied in anxiety-model, stress-response, and neuroimmune research.
Epithalon
Synthetic tetrapeptide (Ala-Glu-Asp-Gly) modeled on pineal epithalamin, studied in telomerase and aging-biology research.
Bacteriostatic Water
Aqueous laboratory research reagent studied as a companion diluent for reconstituting lyophilized peptides in the laboratory.