BioTech Pharma
MGF research vial
regenerative Research

MGF

Also known as: Mechano growth factor, IGF-1Ec E-peptide, MGF C-terminal E-domain

The 24-residue human C-terminal E-domain peptide of the IGF-1Ec (mechano growth factor) splice variant, studied as a reference material in muscle-biology research.
Purity
Batch-specific
Form
Lyophilized powder
Enquiry Sizes
Research vial • Bulk / custom fill (quote required)
Peptide Sequence
YQPPSTNKNTKSQRRKGSTFEERK

Compliance Notice: All products supplied by BioTech Pharma are intended strictly for laboratory research and development use only. They are not intended for human or veterinary use, diagnosis, treatment, or consumption of any kind. By submitting an enquiry, the requester confirms they are a qualified researcher or institution and accepts full responsibility for compliant handling and use.

Configure Your Request

Documentation requests are reviewed against the records available for the applicable lot. Availability, methods, and values must be confirmed for the specific enquiry and are not promised in advance.

Form supplied: Lyophilized powder. Your selections are carried into the quote request automatically.

Overview

Mechano growth factor (MGF) is the name given to a peptide from the C-terminal E-domain of the IGF-1Ec splice variant of insulin-like growth factor 1. This catalog entry is fixed to the native human 24-residue sequence YQPPSTNKNTKSQRRKGSTFEERK, which is the sequence documented for the human E-peptide in the literature.

Because the "MGF" label has been applied to several related constructs — rodent-type sequences and stabilized analogs bearing substitutions such as an arginine-to-histidine change — this product is deliberately anchored to the human native sequence to keep chemical identity unambiguous. Lot-specific analytical documentation may be available and should be confirmed for the applicable material, and stabilized or species variants are handled as separate custom items.

Preclinical and in-vitro studies have studied the human E-peptide in the published literature in the context of muscle progenitor-cell activation following mechanical or exercise-induced stimuli. These model observations are exploratory, do not establish clinical efficacy, and are distinct from established pharmacology; the peptide is supplied only as a research reagent and is not a drug or a product for human or veterinary use.

Research Applications

  • Skeletal-muscle cell-model research
  • Muscle progenitor / satellite-cell activation studies (in vitro)
  • IGF-1 splice-variant and E-peptide biology
  • Exercise- and mechanical-stimulus response research
  • Peptide identity and species-variant characterization

Frequently Asked Questions

Scientific References

Analytical Data

Lot-specific documentation may be available for the applicable material and must be confirmed per enquiry. Where available, it may include:

  • HPLC purity result
  • LC-MS identity confirmation
  • Appearance
  • Net content

Request the records you need with your quote and we will confirm availability for your batch.

Procurement Details

Availability, lead time, salt / content basis, and cold-chain requirements depend on the specific lot and quantity, so we confirm them per enquiry rather than publishing fixed figures. Request confirmation for your requirements with your quote and our team will respond with details for the applicable batch.

Storage & Handling

Lyophilized powder: store desiccated at −20 °C, protected from light and moisture. Reconstitute immediately before use; keep prepared aqueous solutions cold (2–8 °C) and use within an empirically determined stability window for the applicable material.

Related Compounds