2D Molecular Structure
- CID
- 92432
- Standard InChIKey
- JDKLPDJLXHXHNV-MFVUMRCOSA-N
- FDA UNII
- UPF5CJ93X7
- Residue Count
- 7 AA
- Structural Modifications
- N-terminal acetyl (Ac-Nle)
- C-terminal amide
- D-Phe at position 3 (α-MSH position 7)
- Side-chain lactam cyclization (Asp↔Lys)
Melanotan II
Also known as: Melanotan-II, MT-II, MT-2
- CAS Number
- 121062-08-6
- Molecular Formula
- C50H69N15O9
- Molecular Weight
- 1024.2 g/mol
- Purity
- Batch-specific
- Form
- Lyophilized powder
- Enquiry Sizes
- Research vial • Bulk / custom fill (quote required)
- Peptide Sequence7 residues
- Ac-Nle-cyclo[Asp-His-D-Phe-Arg-Trp-Lys]-NH2
Compliance Notice: All products supplied by BioTech Pharma are intended strictly for laboratory research and development use only. They are not intended for human or veterinary use, diagnosis, treatment, or consumption of any kind. By submitting an enquiry, the requester confirms they are a qualified researcher or institution and accepts full responsibility for compliant handling and use.
Configure Your Request
Documentation requests are reviewed against the records available for the applicable lot. Availability, methods, and values must be confirmed for the specific enquiry and are not promised in advance.
Form supplied: Lyophilized powder. Your selections are carried into the quote request automatically.
Overview
Melanotan II is a cyclic synthetic heptapeptide analog of α-melanocyte-stimulating hormone (α-MSH). Cyclization between the aspartate and lysine residues confers metabolic stability and non-selective agonism across melanocortin receptors, making it a widely cited pharmacological tool for probing melanocortin signaling in laboratory models.
Preclinical research on Melanotan II spans melanocortin-receptor (MC1R–MC5R) activation, melanogenesis in cultured melanocytes, and central melanocortin pathways studied in animal models. Its broad receptor engagement is scientifically useful precisely because it is non-selective; this same property is why researchers pair it with more selective analogs to dissect receptor-specific effects.
BioTech Pharma supplies Melanotan II as a lyophilized powder offered strictly for in-vitro and preclinical research; it is not a drug and is not intended for human or veterinary use. Lot-specific analytical documentation may be available and should be confirmed for the applicable material.
Research Applications
- Melanocortin receptor (MC1R–MC5R) agonist pharmacology
- Melanogenesis and melanocyte cell-culture studies
- Central melanocortin signaling in animal models
- Comparative studies with selective melanocortin analogs
Frequently Asked Questions
Scientific References
Analytical Data
Lot-specific documentation may be available for the applicable material and must be confirmed per enquiry. Where available, it may include:
- HPLC purity result
- LC-MS identity confirmation
- Appearance
- Net content
Request the records you need with your quote and we will confirm availability for your batch.
Procurement Details
Availability, lead time, salt / content basis, and cold-chain requirements depend on the specific lot and quantity, so we confirm them per enquiry rather than publishing fixed figures. Request confirmation for your requirements with your quote and our team will respond with details for the applicable batch.
Storage & Handling
Lyophilized: store at −20 °C, protected from light and moisture. Reconstituted: store cold and protected from light; confirm prepared-solution stability for the applicable material before extended use.
Related Compounds
Afamelanotide
Linear [Nle4,D-Phe7]-α-MSH analog and reference melanocortin agonist, studied in melanogenesis and photoprotection research.
GHK-Cu
Naturally occurring copper tripeptide complex, central to dermal-matrix, collagen-synthesis, and cosmetic-formulation research.
Bacteriostatic Water
Aqueous laboratory research reagent studied as a companion diluent for reconstituting lyophilized peptides in the laboratory.