2D Molecular Structure
- CID
- 5485199
- Standard InChIKey
- FHZPGIUBXYVUOY-VWGYHWLBSA-N
- FDA UNII
- 2SEC01B703
- Residue Count
- 7 AA
- Structural Modifications
- Free N-terminus
- C-terminal amide
- D-Ala at position 2
Dermorphin
Also known as: Tyr-D-Ala-Phe-Gly-Tyr-Pro-Ser-NH2
- CAS Number
- 77614-16-5
- Molecular Formula
- C40H50N8O10
- Molecular Weight
- ≈ 802.9 g/mol
- Purity
- Batch-specific
- Form
- Lyophilized powder
- Enquiry Sizes
- Research vial • Bulk / custom fill (quote required)
- Peptide Sequence7 residues
- H-Tyr-D-Ala-Phe-Gly-Tyr-Pro-Ser-NH2
Compliance Notice: All products supplied by BioTech Pharma are intended strictly for laboratory research and development use only. They are not intended for human or veterinary use, diagnosis, treatment, or consumption of any kind. By submitting an enquiry, the requester confirms they are a qualified researcher or institution and accepts full responsibility for compliant handling and use.
Configure Your Request
Documentation requests are reviewed against the records available for the applicable lot. Availability, methods, and values must be confirmed for the specific enquiry and are not promised in advance.
Form supplied: Lyophilized powder. Your selections are carried into the quote request automatically.
Overview
Dermorphin is a naturally occurring heptapeptide (H-Tyr-D-Ala-Phe-Gly-Tyr-Pro-Ser-NH2) first isolated from the skin of South American Phyllomedusa frogs. It is notable for containing a D-alanine residue at position 2 — an unusual feature for a ribosomally encoded peptide — which is associated with its metabolic stability and μ-opioid receptor selectivity.
In pharmacology research it is used as a reference μ-opioid receptor-binding ligand in receptor-binding and functional assays. It is not found in mammals, so it also serves as a reference material for studying D-amino-acid-containing peptides and their biosynthesis. These are model observations and do not establish clinical efficacy.
BioTech Pharma supplies synthetic dermorphin as a C-terminally amidated lyophilized powder offered strictly as a laboratory research reagent; it is not a drug and is not intended for human or veterinary use, and no administration or dosing guidance is provided. Lot-specific analytical documentation may be available and should be confirmed for the applicable material.
Research Applications
- μ-opioid receptor binding and functional assays
- Opioid-agonist selectivity and structure-activity studies
- D-amino-acid peptide chemistry and stability research
- Amphibian host-defense/neuropeptide comparative studies
- Reference-agonist pharmacology work
Frequently Asked Questions
Scientific References
Analytical Data
Lot-specific documentation may be available for the applicable material and must be confirmed per enquiry. Where available, it may include:
- HPLC purity result
- LC-MS identity confirmation
- Appearance
- Net content
Request the records you need with your quote and we will confirm availability for your batch.
Procurement Details
Availability, lead time, salt / content basis, and cold-chain requirements depend on the specific lot and quantity, so we confirm them per enquiry rather than publishing fixed figures. Request confirmation for your requirements with your quote and our team will respond with details for the applicable batch.
Storage & Handling
Lyophilized powder: store desiccated at −20 °C, protected from light and moisture. Reconstitute immediately before use; keep prepared aqueous solutions cold (2–8 °C) and use within an empirically determined stability window for the applicable material.
Related Compounds
Semax
ACTH(4-7)-derived heptapeptide investigated in neuroprotection, cognitive-performance, and BDNF-pathway research.
Selank
Synthetic tuftsin-analog heptapeptide studied in anxiety-model, stress-response, and neuroimmune research.
Bacteriostatic Water
Aqueous laboratory research reagent studied as a companion diluent for reconstituting lyophilized peptides in the laboratory.