2D Molecular Structure
- CID
- 91810664
- Standard InChIKey
- WZTIQQBMSJTRBR-WYKNNRPVSA-N
- FDA UNII
- 9W5677JKDA
- Residue Count
- 11 AA
- Structural Modifications
- N-terminal pyroglutamate (Pyr)
- C-terminal free acid (–OH)
- No disulfide
ARA-290 / Cibinetide
Also known as: Cibinetide, ARA 290, Helix B surface peptide, PH-BSP
- CAS Number
- 1208243-50-8
- Molecular Formula
- C51H84N16O21
- Molecular Weight
- 1257.3 g/mol
- Purity
- Batch-specific
- Form
- Lyophilized powder
- Enquiry Sizes
- Research vial • Bulk / custom fill (quote required)
- Peptide Sequence11 residues
- Pyr-Glu-Gln-Leu-Glu-Arg-Ala-Leu-Asn-Ser-Ser (N-terminal pyroglutamate)
Compliance Notice: All products supplied by BioTech Pharma are intended strictly for laboratory research and development use only. They are not intended for human or veterinary use, diagnosis, treatment, or consumption of any kind. By submitting an enquiry, the requester confirms they are a qualified researcher or institution and accepts full responsibility for compliant handling and use.
Configure Your Request
Documentation requests are reviewed against the records available for the applicable lot. Availability, methods, and values must be confirmed for the specific enquiry and are not promised in advance.
Form supplied: Lyophilized powder. Your selections are carried into the quote request automatically.
Overview
Cibinetide (ARA-290) is an engineered 11-amino-acid peptide, beginning with an N-terminal pyroglutamate, designed to mimic the three-dimensional helix-B surface domain of erythropoietin (EPO). Its defined structure (C51H84N16O21; 1257.3 g/mol) is documented in the PubChem compound record.
The peptide is designed to bind selectively to the non-hematopoietic, tissue-protective receptor thought to be a heterocomplex of the EPO receptor and the beta-common receptor (CD131), rather than the classical hematopoietic EPO receptor. In preclinical and early clinical research it has been examined for tissue-protective and anti-inflammatory signaling and in neuropathic-pain models. These are research findings; the molecule is investigational and its therapeutic value is not established.
BioTech Pharma supplies ARA-290 / cibinetide as a lyophilized powder offered strictly as a laboratory reference peptide; it is not a drug or a product for human or veterinary use. Lot-specific analytical documentation may be available and should be confirmed for the applicable material.
Research Applications
- Non-hematopoietic (innate repair receptor) EPO signaling
- Tissue-protective and anti-inflammatory pathway research
- Neuropathic-pain and small-fiber model studies
- EPO structure-mimetic peptide design
- Cytokine and immune-modulation research models
Frequently Asked Questions
Scientific References
Analytical Data
Lot-specific documentation may be available for the applicable material and must be confirmed per enquiry. Where available, it may include:
- HPLC purity result
- LC-MS identity confirmation
- Appearance
- Net content
Request the records you need with your quote and we will confirm availability for your batch.
Procurement Details
Availability, lead time, salt / content basis, and cold-chain requirements depend on the specific lot and quantity, so we confirm them per enquiry rather than publishing fixed figures. Request confirmation for your requirements with your quote and our team will respond with details for the applicable batch.
Storage & Handling
Lyophilized: store sealed at −20 °C, protected from light and moisture. Reconstituted solutions should be kept refrigerated (2–8 °C); prepared-solution stability is lot-specific and should be verified empirically for each protocol. Prepared-solution stability should be confirmed for the applicable material.
Related Compounds
Thymosin Alpha-1
N-acetylated 28-residue immunomodulatory peptide derived from prothymosin alpha, studied in immune-signaling and tissue-response research.
BPC-157
Pentadecapeptide derived from gastric Body Protection Compound, widely studied in tissue-repair and gastrointestinal research models.
GHK-Cu
Naturally occurring copper tripeptide complex, central to dermal-matrix, collagen-synthesis, and cosmetic-formulation research.