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Adipotide research vial

2D Molecular Structure

Adipotide 2D molecular structure for compound 163360068
CID
163360068
Standard InChIKey
GZESIPHLGJDZRG-VCWDIOOSSA-N
Residue Count
25 AA
Structural Modifications
  • Reduced di-thiol form (two free Cys -SH; no disulfide)
  • D-amino-acid KLAKLAK proapoptotic domain
  • Gly-Gly linker between homing and effector domains
metabolic Research

Adipotide

Also known as: Prohibitin-targeting peptide 1, FTPP, Prohibitin-TP01, TP01

Peptidomimetic conjugate (CKGGRAKDC homing motif linked to a D-amino-acid proapoptotic domain) studied in adipose-vasculature research models.
CAS Number
859216-15-2
Molecular Formula
C111H206N36O28S2
Molecular Weight
≈ 2557.2 g/mol
Purity
Batch-specific
Form
Lyophilized powder
Enquiry Sizes
Research vial • Bulk / custom fill (quote required)
Peptide Sequence25 residues
CKGGRAKDC-GG-D(KLAKLAK)2

Compliance Notice: All products supplied by BioTech Pharma are intended strictly for laboratory research and development use only. They are not intended for human or veterinary use, diagnosis, treatment, or consumption of any kind. By submitting an enquiry, the requester confirms they are a qualified researcher or institution and accepts full responsibility for compliant handling and use.

Configure Your Request

Documentation requests are reviewed against the records available for the applicable lot. Availability, methods, and values must be confirmed for the specific enquiry and are not promised in advance.

Form supplied: Lyophilized powder. Your selections are carried into the quote request automatically.

Overview

Adipotide, also called prohibitin-targeting peptide 1 (TP01), is a peptidomimetic with the sequence CKGGRAKDC-GG-D(KLAKLAK)2. This catalog identity is anchored to the reduced, linear di-thiol form represented by PubChem CID 163360068. Its CKGGRAKDC homing motif — reported to recognize prohibitin and annexin A2 on the vasculature of white adipose tissue — is joined to a D-amino-acid proapoptotic KLAKLAK domain through a glycine-glycine linker.

In published preclinical studies the conjugate was investigated for its ability to act on the blood supply of adipose tissue in rodent and non-human-primate models. Clinical development of the compound was discontinued, and these findings remain preclinical observations rather than established pharmacology.

BioTech Pharma supplies adipotide as a lyophilized powder for laboratory research use only. The two cysteine thiols can oxidize to a disulfide-cyclized state, which is a distinct molecular form from the reduced PubChem structure shown here; the characterized redox state, where available, should be confirmed in lot-specific analytical documentation for the applicable material.

Research Applications

  • Adipose-tissue vasculature targeting models
  • Prohibitin and annexin A2 ligand-recognition studies
  • Proapoptotic (KLAKLAK) domain mechanism research
  • Homing-peptide conjugate structure-activity work
  • Comparative metabolic-model pharmacology

Frequently Asked Questions

Scientific References

Analytical Data

Lot-specific documentation may be available for the applicable material and must be confirmed per enquiry. Where available, it may include:

  • HPLC purity result
  • LC-MS identity confirmation
  • Appearance
  • Net content

Request the records you need with your quote and we will confirm availability for your batch.

Procurement Details

Availability, lead time, salt / content basis, and cold-chain requirements depend on the specific lot and quantity, so we confirm them per enquiry rather than publishing fixed figures. Request confirmation for your requirements with your quote and our team will respond with details for the applicable batch.

Storage & Handling

Lyophilized powder: store desiccated at −20 °C, protected from light and moisture. Reconstitute immediately before use; keep prepared aqueous solutions cold (2–8 °C) and use within an empirically determined stability window for the applicable material.

Related Compounds