2D Molecular Structure
- CID
- 53314964
- Standard InChIKey
- VBUWHHLIZKOSMS-RIWXPGAOSA-N
- FDA UNII
- 6J2WVD66KR
- Residue Count
- 28 AA
- Structural Modifications
- Free N-terminus
- C-terminal amide
- Contains oxidation-sensitive Met
VIP (Vasoactive Intestinal Peptide)
Also known as: Vasoactive Intestinal Peptide, Aviptadil, VIP 1-28
- CAS Number
- 40077-57-4
- Molecular Formula
- C147H237N43O43S
- Molecular Weight
- 3326.8 g/mol
- Purity
- Batch-specific
- Form
- Lyophilized powder
- Enquiry Sizes
- Research vial • Bulk / custom fill (quote required)
- Peptide Sequence28 residues
- His-Ser-Asp-Ala-Val-Phe-Thr-Asp-Asn-Tyr-Thr-Arg-Leu-Arg-Lys-Gln-Met-Ala-Val-Lys-Lys-Tyr-Leu-Asn-Ser-Ile-Leu-Asn-NH2
Compliance Notice: All products supplied by BioTech Pharma are intended strictly for laboratory research and development use only. They are not intended for human or veterinary use, diagnosis, treatment, or consumption of any kind. By submitting an enquiry, the requester confirms they are a qualified researcher or institution and accepts full responsibility for compliant handling and use.
Configure Your Request
Documentation requests are reviewed against the records available for the applicable lot. Availability, methods, and values must be confirmed for the specific enquiry and are not promised in advance.
Form supplied: Lyophilized powder. Your selections are carried into the quote request automatically.
Overview
Vasoactive intestinal peptide (VIP) is a 28-amino-acid, C-terminally amidated neuropeptide belonging to the secretin/glucagon peptide superfamily. First described for its vasodilatory action in the gut, it is now recognized as a broadly distributed signaling peptide that acts through the class-B G-protein-coupled receptors VPAC1 and VPAC2.
As an endogenous hormone, VIP has well-characterized physiology: it participates in smooth-muscle relaxation, secretory regulation, circadian signaling in the suprachiasmatic nucleus, and immunomodulation. In research it serves as a reference VPAC-receptor agonist for binding assays, cAMP-signaling studies, and comparative neuropeptide pharmacology. The synthetic form supplied here is identical in sequence to the human peptide.
BioTech Pharma supplies VIP as a lyophilized powder for in-vitro and preclinical research use only; it is not a drug and is not intended for human or veterinary use. The sequence contains an oxidation-sensitive methionine residue. Lot-specific analytical documentation may be available and should be confirmed for the applicable material.
Research Applications
- VPAC1 / VPAC2 receptor binding and cAMP signaling assays
- Gut-hormone and GI smooth-muscle research
- Circadian and suprachiasmatic-nucleus neurobiology
- Neuroimmunology and immunomodulation studies
- Secretin/glucagon-superfamily comparative pharmacology
Frequently Asked Questions
Scientific References
Analytical Data
Lot-specific documentation may be available for the applicable material and must be confirmed per enquiry. Where available, it may include:
- HPLC purity result
- LC-MS identity confirmation
- Appearance
- Net content
Request the records you need with your quote and we will confirm availability for your batch.
Procurement Details
Availability, lead time, salt / content basis, and cold-chain requirements depend on the specific lot and quantity, so we confirm them per enquiry rather than publishing fixed figures. Request confirmation for your requirements with your quote and our team will respond with details for the applicable batch.
Storage & Handling
Lyophilized: store at −20 °C, protected from light and moisture; the methionine residue is oxidation-sensitive, so limit air exposure. Reconstituted: store cold and protected from light; VIP is a large peptide sensitive to freeze-thaw, so confirm prepared-solution stability for the applicable material before extended use.
Related Compounds
Kisspeptin-10
KISS1-derived decapeptide and master regulator of the reproductive axis — the key tool compound in GnRH-pathway research.
Tesamorelin
Stabilized GHRH analog used in growth-hormone-axis research, engineered for resistance to enzymatic degradation.
Bacteriostatic Water
Aqueous laboratory research reagent studied as a companion diluent for reconstituting lyophilized peptides in the laboratory.